Vitamin B12, Cobalt

Vitamin B12 is an essential nutrient in the B-complex of water soluble vitamins.

This nutrient must be consumed through animal foods, to ensure adequate intake. Supplements are recommended, due to lack of cobalt in the bio-system!!  B12 is the most complex of all the vitamins and has an awesome power in human health. It is needed for normal energy metabolism in all cells of the body, including amino acid and fatty acid metabolism. B12 is also known as “cobalamin” and is important in vital physiological  processes as brain functioning, and nervous system health; production of myelin sheath to insulate the nerve fibers. Also formation of red blood cells and bone marrow, including DNA regulation and synthesis. It is produced by certain colon bacteria. B12 is needed as a minium Daily Recommended Intake {DRI} of 2 to 7 micro grams per day. B12 is safe at higher doses when used to prevent poisoning from arsenic.

The body can store up to 3-5 years worth of B12 because the Liver recycles B12. Deficiency does not show up for years until the reserves in the Liver are used up, due to lack of intake.When testing the blood the normal range is 180 to 900ng/L, however B12 less than 500 pico gram may produce deficiency. To ensure optimal health of your brain and nervous system, blood testing is important! Lack of B12 increases the level of homocyteine and decreases the synthesis of DNA!! The deficiency also may cause macrocytic anemia, peripheral neuropathy, neurological disorders, ie, cognitive decline, loss of mobility and balance.

Long standing deficiency may be irreversible!! Low stomach acid may cause a deficiency of B12 , for the acid is needed to break the bond that B12 has on the proteins in food. The Elderly tend to have low stomach acid. Also Celiac disease my impair absorption of B12 in the ileum of the small intestine. Bad bacteria over growth can cause mal-absorption of B12, parasitic infection from Giardiasis may cause deficiency. Also genetic factor may cause deficiency, as does excessive alcohol intake!!

Sources of B12: Clams,organ meats especially liver, beef, turkey, fish, eggs, mackerel, and crab meat.


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Vitamin B3, Niacin

Niacin is essential to good health of the human body. The formula C6H5NO2 is basic, however, extremely important to regulating over 450 functions in the body, including, high blood cholesterol, via improving Good cholesterol and lowering bad cholesterol.

Niacin also prevents Pellagra, an extremely deadly disease, back in 1940s when the connection between Niacin and Pellagra was unknown, 100,000 people each year died due to lack of Niacin! Niacin can cause a flush of blood with a tingling sensation, to prevent this, another form of Niacin is used called Niacinamide. All types of Niacin should be taken with equal dosages of Vitamin C. This lowers the level of Histamine, thus preventing Anaphylactic Shock. This could happen if a person is sensitive to a certain protein.

The new DV daily value for Niacin is 16 mg, this is extremely low, it only prevents outright disease, and is not enough for optimum health. 75 mg to 250 mg Niacin is recommended for active people.

Niacin also helps “ADD” Attention Deficit Disorder and Lupus at higher doses near 1,000 mg per day up to 3,000 mg per day divided between three meals including Vitamin C at similar doses. Arthritis has shown improvement with 250 mg Niacinamide three times a day. Improvements in some forms of Pellagra induced Schizophrenics have recovery rates near 90% when on 3,000 mg Niacin and 10,000 mg of Vitamin C.

A new form of B3 called Nicotinamide Riboside acts to increase NAD+ , this mimics a calorie restricted diet that fine tunes our metabolic system, to burn fat and improve insulin sensitivity.

To learn more about Niacin read: NIACIN, The Real Story, by Abram Hoffer M.D. Ph.D., Andrew W. Saul Ph.D., and  Harold D. Foster Ph.D.


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Vitamin E, Fat Anti Oxidant

Vitamin E exists in eight forms, however, the Liver only uses d-alpha-tocopherol, the other seven forms are removed from the body (excreted ); also the synthetic Vitamin E, dl-alpha-tocopherol is half “Left Hand” and half “Right Hand” due to the chemistry of making it synthetically. Your body can not use the ” Left Handed” version, so it is only half as effective. It makes sense to only buy the Natural “Right  Handed” Vitamin E which is d-alpha-tocopherol. Otherwise You are wasting Your money on types of Vitamin E that Your body can not use!

Vitamin E is a very powerful Anti Oxidant protecting cells from the damaging effects of free radicals, which are, molecules that contain an unshared electron. Free radicals may cause the development of Cancers and Cardiovascular diease. The electrons are Very Energetic, forming reactive Oxygen, called ROS, “Reactive Oxygen Species”, ( as a result of converting food into energy and Free Radicals, as a by product). Anti Oxidant Vitamin E protects cells from damage by nuetralizing the energetic electrons in the Free Radicals and the Reactive Oxygen.  Once Vitamin E nuetralizes a Free Radical, it must be re-activated by Vitamin C to be able to again neutralize another Free Radical. Together Vitamin E and Vitamin C help Your body to prevent damage to Your cells.Also Vitamin E is involved with the immune system and regulation of gene expression and dilation of blood vessels, including inhibiting platelet aggregation ( clotting).

The “Recommended Dietary Allowances” RDA  for 18 year olds is 22.5 IU ( international units) this is a minium, and not for Maximum Preformance. The Upper limit is 1,500 IU. Normally 400 to 800 IU is great for the non- athlete.It should be remembered that Vitamin E inhibits platelet aggregation ( clotting ), thus antagonizes K dependent clotting factors. This may increase the risk of bleeding with the use of Warfarin ( Coumadin ).

Vitamin E is naturally found in Nuts, green Leafy Vegetables, Whole Grains, Fruits and Oils including eggs, lean meats, seafood, beans, and peas. Adding supplements that contain Vitamin E ensures You have enough for Maximum preformance.

 

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Vitamin C, Super Anti Oxidant

Vitamin C ( L- ascorbic acid, water soluble ) is an essential dietary requirement, because unlike most animals that make Vitamin C, Humans can not make their own Vitamin C. Vitamin C is required to make Collagen, to form connective tissue to hold the body together including teeth in their sockets; also L-Caritine an amino acid used to build Proteins; and Vitamin C is used to make Neurotransmitters.

Vitamin C regenerates another Anti Oxidant Vitamin E ( fat soluble, alpha-tocopherol ) together they fight Free radicals through out the body, helping to prevent Cancer, Heart disease and cardiovascular disease. This helps the Immune system fight off invaders to the body. Insufficient Vitamin C causes Scurvy, fatigue, lassitude, weakness, and Capillary Fragility. The RDA requirement is 60 mg for Adults, however, to achieve optimal blood plasma levels 250 mg should be taken. If You are ill that should be increased to 1250 mg of Vitamin C ( daily), then when You are well back to 250 mg to prevent Oxalates from forming that could lead to kidney stones! Clinical studies have shown Vitamin C reduces the risk of Stroke and Age related Macular  degeneration, also lowers risk of Cataracts.

Many Foods contain Vitamin C, including Red Peppers 1/2 cup 95mg, Citrus fruits  one medium 70mg, Kiwi fruit 64mg, Strawberries 1/2 cup 49mg, Cantaloupe 1/2 cup 29mg, and Broccoli 1/2 cup 51mg, to name a few. In todays modern diet of fast foods One has a hard time getting enough Vitamin C. Supplements make it easy to keep the minium of 250mg per day do-able.

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Enzymes, Run the Gut

Enzymes are the under reported part of Your body’s system that starts at the mouth, with alpha- Amylase to start Hydrolyses of starches and complex sugars, digesting them into simple sugars like glucose.

Then later, Protease is added to digest proteins after the stomach acids start the process, into peptides then amino acids. Then Lipase is added to catalyze the hydrolysis of fats, digesting them into fatty acids.This process continues down the small intestines where Cellulase ( from fungi, bacteria and protozoa ) breaks down fiber. There are over 3000 enzymes that catalyze the many reactions in the Gut and through out the body. The Pancreas produces enzymes and stores them for later use, it is also part of the recycling system that takes the enzymes back out of the Gut into the Blood system via inhibitors that de-activate the Enzymes, to return to the Pancreas to be used again. The loss of some Enzymes happens and must be replaced by the Pancreas. This can over load the Pancreas if large meals tax the system. Therefore using supplemental Enzymes keeps the Pancreas from damage.

The major part of Enzymes job includes working with the immune system. The antigen ( foreign body ,i.e. virus, bacteria, fungus, debris ) activates the antibodies to attack the invader, grabbing it to form immune complexes, normally Macrophages are called to surround the immune complexes and neutralize them. However, if overloaded with invaders the job falls to the Enzymes to neutralize the immune complexes. Immune complexes can be found in the blood stream system and in tissue; this situation calls for the Enzymes to go into action, neutralizing the offending agent.

The Europeans have been using oral Enzyme supplements to stabilize MS ( Multiple Sclerosis ) and improve many forms of Arthritis. For more information on these groundbreaking discovers read: Enzymes, The Fountain of Life,  by D.A. Lopez, M.D.  R.M. Williams, M.D.,  Ph.D,  K. Miehllke, M.D.

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Fish Oil, Omega 3

Fish Oil, Omega 3s are the KEY agent to vastly improving your Health and Wellness. Omega 3s are required to compete your cell walls, with out Omega 3s the cell is open to being invaded by viruses, bacteria, and fungus.

The ancient diet had a ratio of 4 to 1 omega 3, now it is only 20 to 1 omega 3. This is a 5 fold reduction! Omega 3s are paramount to reducing inflammation through out Your body, including the Heart, veins, and arteries. Over time Omega 3s improve blood flow and help remove blood clots, reducing the odds of Stroke and Heart attack! The two main forms are DHA ( Docosahexaenoic acid ) and EPA ( Eicosapentaenoic acid ), combined dose 2000 mg approximately. Some people find Fish Oil hard to take, there is a Plant based form, ALA ( alpha-Linolenic acid ) from Flax seed. Also Krill Oil contains Omega 3s in a different matrix, however, allergic reactions, hives, breathing problems, swelling, etc. can occur! Check to be sure no Mercury or PCBs ( polychlorinate biphenyls ) are in the supplements. Of course you can eat more fish, especially, anchovy, sardine, mackerel, herring, and trout. A High Quality Omega 3 supplement is more cost effective and safer. Also as a bonus Omega 3s improve your mood, as a report from University of Michigan Depression Center states in their Depression Tool Kit.

 


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Mitochondria, Mighty Motors

mitochondria

Mitochondria produce the energy that runs our cells, converting ADP ( adenosine5′-diphosphate ) to ATP ( adenosine triphosphate ) using the Krebs Cycle ( citric acid cycle ) via an electron transport chain. The process combines Oxygen with the food we eat to produce the energy to make ATP. This aerobic system is very efficient giving us 90% of our energy, the other 10% is produced by an anaerobic ( without Oxygen ) process that is not efficient and produces Lactic acid that must be acted on later.

There are two agents Acetyl-L-Carnitine and Alpha Lipoic Acid that are major supporters in the above process. Acetyl-L-Caritine combines with CoA ( Coenzyme A ) to produce acetyl-CoA that enters the Krebs cycle powering the conversion of ATP, by giving up the acetyl group; CoA goes back to be recharged by Acetyl-L-Carnitine. Similarly Alpha-Lipoic Acid is a co-factor in two enzyme systems that are also used in the Krebs cycle to produce energy from food (carbs). Alpha-Lipoic Acid is in food, however in very small amounts. The use of supplemental ALA ( Alpha-Lipoic-Acid ) and ALC  ( Acetyl-L-Carnitine ) has been very beneficial in enhancing the Mitochondria to stay healthy.One formulation OTC shows  ALC at 500 mg and ALA at 200 mg.

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Garlic, Nature’s Antibiotic, Anti-fungal, Anti-Viral, Herb

Garlic is one of Natures gifts to all people. The many cultures Egyptian, Chinese, Greek, and Roman, all used Garlic. It is a member of the Allium ( Onion ) family. The active agent is Allicin  (C6 H10 OS2 ). Allicin is produced by the Garlic plant when attacked, changing Alliin to Allicin, thus fending off the insect or microbe that attacked using the powerful sulfur atom in its make up. This action has been used by Man/Woman to fight off many attackers from the Human body, including Fungus and Viral attack. The present day battles with Colds and Flu take more than 40,000 people away just in USA alone, ever year. Garlic has been shown to help fight against these enemy vectors. The many uses of fresh and prepared garlic fill many recipe books. However by using high dose Allicin supplements you can protect yourself from many seasonal ailments. Being Healthy and Happy is everyones goal.
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Turmeric, Old Spice, Super Herb

Turmeric has been used for thousands of years, mostly in India and South Asia. This spice is a member of the ginger family, and has many helpful properties. The spice has very powerful anti-inflammatory action on the body, reducing the pain of peripheral nerve damage, and calming the lining of the veins and arteries, allowing the blood to flow freely. It is also an antioxidant, working with vitamins E and C. The pain of Arthritis is reduced by its action. Turmeric is also an anti -coagulant ( similar to Aspirin).

When taking Turmeric you should take pepperine the active part of Black Pepper, it improves the absorption by 30%. The active part of Turmeric is Curcumin along with other curcuminoids.

Turmeric root  turmeric

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Vitamin D, the Sun Shine Vitamin

Vitamin D has become interesting in that over 60% of the population is deficient, not to the point of disease. However, causing sub-clinical problems. The scale zero to 100, with 30 being the minimum desired and 60 nmol/l the target for,  normal individual, with athletes the range is  90 nmol/l to 120.

Most people are below 30 nmol/l. The form used in supplements is D3, it is active in the body preventing diseases including Rickets, bone diseases, and muscle weakness. Most everyone should be tested to ensure their serum levels are above 30 nmol/l.

Along with D3 a forgotten Vitamin K2 has been re-discovered, that directs the D3 to deposit its Calcium load in the bones and, not in the veins where it can restrict blood flow. The use of K2 with D3 should be obvious! K2 can be found in hard cheeses, especially Gouda cheese, or supplements, 100 mcg K2 for each 10,000 IU of D3. Do not confuse K1 for K2, as K1 is for preventing blood thinning, it helps to clot the blood.  Also you must have enough magnesium and calcium in your diet or supplements to support the D3 !

Anecdotal evidence has suggested that D3 may be much more important than previously realized. It could improve many conditions not yet verified.While we wait it would be good to keep our levels above the target of 60 nmol/l.

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